Kelch Like ECH Associated Protein 1 (KEAP1) Antibody

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain.Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus.This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Target	Kelch Like ECH Associated Protein 1 (KEAP1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human KEAP1 (AA: 380-624) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14145 (UniProt, ExPASy)
UniProt Secondary AC	B3KPD5, Q6LEP0, Q8WTX1, Q9BPY9
UniProt Entry Name	KEAP1_HUMAN
Gene Symbol	KEAP1
GeneID	9817
OMIM	606016
HGNC	23177
KEGG	hsa:9817
Ensembl	ENSG00000079999
String	9606.ENSP00000171111
Molecular Weight	69.7 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Kelch Like ECH Associated Protein 1 (KEAP1)

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