KRT8 (pS74) Antibody

Catalogue No: abx000433
Price: £220.00
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KRT8 (pS74) Antibody
KRT8 (pS74) Antibody

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KRT8 (pS74) Antibody is a Rabbit Polyclonal antibody against KRT8 (pS74). This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Target KRT8 (pS74)
Reactivity Human
Origin Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IF/ICC
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S74 of human KRT8.
Purification Affinity purified.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight 55 kDa
Swiss Prot P05787
GeneID 3856
Gene Symbol KRT8
Concentration > 1 mg/ml
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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