LAMBDA Antibody (FITC)

Catalogue No: abx200546
Price: £400.00
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Human immunoglobulins are glycoproteins composed of two disulfide-bonded heavy (H) chain subunits, each of which is linked by interchain disulfide bonds to a light (L) chain forming a tetramolecular complex. There are five classes of immunoglobulins, designated IgG, IgA, IgM, IgD and IgE, which are defined by differences in the constant region of H chains. L chains are divided into kappa or lambda classifications based on structural antigenic differences. All classes of immunoglobulins have been found on the cell surface of B lymphocytes where they function as antigen receptors to elicit antigen-dependent proliferation and secretion of antigen specific soluble circulating antibodies.

The evaluation of cell surface Kappa/Lambda expression can identify clonally restricted B lymphocyte populations and thus can aide in the diagnosis of hematologic malignancy. Several B cell disorders are associated with decreased levels of Kappa/Lambda at the cell surface.

Reactivity Human
Host Rabbit
Clonality Polyclonal
Tested Applications FCM
Recommended dilutions FCM: 10 µl/1 million cells. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Polyclonal immunoglobulin light chains of lambda type isolated from a pool of human sera for Rabbit Anti-Human Lambda Light Chain.
Purification Affinity Chromatography
Form Liquid
Isotype IgG
Conjugation FITC
Storage Aliquot and store in the dark at 2°C to 8°C. Avoid exposure to light.
Buffer The reagent is provided in aqueous buffered solution containing protein stabilizer, and 0.09% sodium Azide
UNSPSC Code 12352203
Availability Shipped within 1-2 weeks.
Note This product is for research use only.

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