Low Density Lipoprotein Receptor Related Protein Associated Protein 1 (LRPAP1) Antibody

LRPAP1 Antibody is a Rabbit Polyclonal antibody against LRPAP1. Low density lipoprotein receptor-related protein associated protein 1 also known as LRPAP1 or RAP is a chaperone protein which in humans is encoded by the LRPAP1 gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.

Target	Low Density Lipoprotein Receptor Related Protein Associated Protein 1 (LRPAP1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human LRPAP1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30533 (UniProt, ExPASy)
UniProt Secondary AC	D3DVR9, Q2M310, Q53HQ3, Q53HS6
UniProt Entry Name	AMRP_HUMAN
Gene Symbol	LRPAP1
GeneID	4043
KEGG	hsa:4043
String	9606.ENSP00000421922
Molecular Weight	Calculated MW: 41 kDa Observed MW: 39 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Low Density Lipoprotein Receptor Related Protein Associated Protein 1 (LRPAP1)

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