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MAPK14 (pT180 / Y182) Antibody

Catalogue No: abx000348
Price: £120.00
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MAPK14 (pT180/Y182) Antibody is a Rabbit Polyclonal antibody against MAPK14 (pT180/Y182). The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Target MAPK14 (pT180/Y182)
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T180/Y182 of human MAPK14.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q16539 (UniProt, ExPASy)
UniProt Entry Name MK14_HUMAN
Gene Symbol MAPK14
GeneID 1432
String 9606.ENSP00000229795
Molecular Weight Calculated MW: 29 kDa, 34 kDa, 35 kDa, 41 kDa
Observed MW: 41 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MAPK14 (pT180 / Y182) Antibody

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