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Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody

Catalogue No: abx011122
Price: £290.00
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Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody

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Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF alpha 1 and forskolin.

Target Induced Myeloid Leukemia Cell Differentiation Protein (MCL1)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, IF/ICC
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human MCL-1 expressed in E. Coli.
Isotype IgG1
Form Liquid
Purification Purified from ascites by Protein G chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q07820 (UniProt, ExPASy)
UniProt Entry Name MCL1_HUMAN
Gene Symbol MCL1
GeneID 4170
OMIM 159552
HGNC 6943
KEGG hsa:417
Ensembl ENSG00000143384
String 9606.ENSP00000358022
Molecular Weight 37 kDa
Buffer PBS, containing 0.03% sodium azide.
Concentration 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Induced Myeloid Leukemia Cell Differentiation Protein (MCL1) Antibody

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