DNA Replication Licensing Factor MCM2 (MCM2) Antibody

Catalogue No: abx000733
Price: £120.00
(Size: 20 µl)
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MCM2 Antibody is a Rabbit Polyclonal antibody against MCM2. The MCM2-7 complex forms the core of the replicative helicase which acts as the molecular motor that uses ATP binding and hydrolysis to fuel the unwinding of double-stranded DNA at the replication fork in eukaryotes. This complex is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. MCM2, also named CDCL1 and BM28, is a human nuclear protein that plays an important role in 2 crucial steps of the cell cycle, namely, onset of DNA replication and cell division.

Target MCM2
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MCM2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P49736 (UniProt, ExPASy)
UniProt Secondary AC Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7
UniProt Entry Name MCM2_HUMAN
Gene Symbol MCM2
GeneID 4171
KEGG hsa:4171
String 9606.ENSP00000265056
Molecular Weight Calculated MW: 101 kDa
Observed MW: 120 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MCM2

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