Dimethyl-Histone H3-K14 Antibody

Dimethyl-Histone H3-K14 Antibody is a Rabbit Polyclonal antibody against Dimethyl-Histone H3-K14. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Target	Dimethyl-Histone H3-K14
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic monomethylated peptide around K14 of human MonoMethyl-Histone H3-K14.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16695 (UniProt, ExPASy)
UniProt Secondary AC	B2R5K3, Q6FGU4
UniProt Entry Name	H31T_HUMAN
Gene Symbol	HIST3H3
GeneID	8290
NCBI Accession	NP_003520.1
KEGG	hsa:8290
String	9606.ENSP00000355657
Molecular Weight	Calculated MW: 16 kDa Observed MW: 17 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Dimethyl-Histone H3-K14

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