MutY Homolog (MUTYH) Antibody

Catalogue No: abx001356
Price: £120.00
(Size: 20 µl)
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MUTYH Antibody is a Rabbit Polyclonal antibody against MUTYH. This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Target MUTYH
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications IHC, IF/ICC
Host Rabbit
Recommended dilutions IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MUTYH.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9UIF7 (UniProt, ExPASy)
UniProt Secondary AC D3DPZ4, Q15830, Q9UBP2, Q9UBS7, Q9UIF4, Q9UIF5, Q9UIF6
UniProt Entry Name MUTYH_HUMAN
Gene Symbol MUTYH
GeneID 4595
String 9606.ENSP00000361170
Molecular Weight Calculated MW: 57 kDa, 58 kDa, 59 kDa, 60 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MUTYH

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