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MYC (pS62) Antibody

Catalogue No: abx000457
Price: £220.00
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MYC (pS62) Antibody is a Rabbit Polyclonal antibody against MYC (pS62). The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Target MYC (pS62)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications IF/ICC
Host Rabbit
Recommended dilutions IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S62 of human MYC.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01106 (UniProt, ExPASy)
UniProt Secondary AC A8WFE7, P01107, Q14026
UniProt Entry Name MYC_HUMAN
Gene Symbol MYC
GeneID 4609
String 9606.ENSP00000479618
Molecular Weight Calculated MW: 48 kDa, 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on MYC (pS62) Antibody

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