NBN (pS343) Antibody

Catalogue No: abx000460
Price: £220.00
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NBN (pS343) Antibody

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NBN (pS343) Antibody is a Rabbit Polyclonal antibody against NBN (pS343). Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Target NBN (pS343)
Reactivity Human
Origin Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S343 of human NBN.
Purification Affinity purified.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight 95 kDa
Swiss Prot O60934
GeneID 4683
Gene Symbol NBN
Concentration > 1 mg/ml
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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