NBN (pS343) Antibody

Catalogue No: abx000460
Price: £230.00
(Size: 50 µl)
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NBN (pS343) Antibody

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NBN (pS343) Antibody is a Rabbit Polyclonal antibody against NBN (pS343). Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Target NBN (pS343)
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S343 of human NBN.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O60934 (UniProt, ExPASy)
UniProt Secondary AC B2R626, B2RNC5, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2
UniProt Entry Name NBN_HUMAN
Gene Symbol NBN
GeneID 4683
KEGG hsa:4683
String 9606.ENSP00000265433
Molecular Weight Calculated MW: 84 kDa
Observed MW: 85 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on NBN (pS343) Antibody

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