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Cytoplasmic Protein NCK1 (NCK1) Antibody

Catalogue No: abx000569
Price: £260.00
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NCK1 Antibody is a Rabbit Polyclonal antibody against NCK1. NCK family adaptor proteins function to couple tyrosine phosphorylation signals to regulate actin cytoskeletal reorganization that leads to cell motility. Cytoplasmic protein NCK1 (or NCK alpha) is an adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. NCK1 binds a number of intracellular proteins and influences various signaling pathways including GTPase-activating protein of Ras (RasGAP), which is responsible for the down-regulation of Ras. NCK1 is recently reported to regulate the UPR, which secondary to obesity impairs glucose homeostasis and insulin actions.

Target NCK1
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human NCK1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC P16333 (UniProt, ExPASy)
UniProt Secondary AC B7Z751, D3DNE3
UniProt Entry Name NCK1_HUMAN
Gene Symbol NCK1
GeneID 4690
String 9606.ENSP00000417273
Molecular Weight Calculated MW: 35 kDa, 42 kDa
Observed MW: 48 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cytoplasmic Protein NCK1 (NCK1) Antibody

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