Alpha-1-Acid Glycoprotein 1 (ORM1) Antibody

Orosomucoid 1 Antibody is a Rabbit Polyclonal antibody against Orosomucoid 1. Alpha-1-acid glycoprotein 1 (AGP1), also called orosomucoid-1 (Orosomucoid 1), is a glycoprotein synthesized mostly by hepatocytes and present in human plasma. Orosomucoid 1 is an acute-phase reactant protein controlled by glucocorticoids, interleukin-1 and interleukin-6, and increase up to 5-50 times upon infection and/or inflammation. Anti-apoptotic effect and role as immunomodulator of ORM have been reported. ORM is an important carrier for synthetic drugs and influences their distribution and availability in the body. This antibody recognizes a band about 44 kDa in human plasma which may be due to the glycosylation of Orosomucoid 1 or the dimer formation of the protein.

Target	Alpha-1-Acid Glycoprotein 1 (ORM1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 35-201 of human ORM1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P02763 (UniProt, ExPASy)
UniProt Secondary AC	B7ZKQ5, Q5T539, Q5U067, Q8TC16
UniProt Entry Name	A1AG1_HUMAN
Gene Symbol	ORM1
GeneID	5004
OMIM	138600
NCBI Accession	NP_000598.2
HGNC	8498
KEGG	hsa:5004
Ensembl	ENSG00000229314
String	9606.ENSP00000259396
Molecular Weight	Calculated MW: 24 kDa Observed MW: 40 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alpha-1-Acid Glycoprotein 1 (ORM1)

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