PAK1 / 2 / 3 (pT423 / 402 / 421) Antibody

Catalogue No: abx000472
Price: £220.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

PAK1 / 2 / 3 (pT423 / 402 / 421) Antibody

Available Options

* Size:

PAK1/2/3 (pT423/402/421) Antibody is a Rabbit Polyclonal antibody against PAK1/2/3 (pT423/402/421). The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

Target PAK1/2/3 (pT423/402/421)
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Tested Applications IHC, IF/ICC
Recommended dilutions IHC: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T423/402/421 of human PAK1/2/3.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 60 kDa, 61 kDa, 58 kDa, 62 kDa, 64 kDa
Swiss Prot Q13153 Q13177 O75914
GeneID 5058/ 5062/ 5063
Gene Symbol PAK1, PAK2, PAK3
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on PAK1 / 2 / 3 (pT423 / 402 / 421) Antibody

Write a review

Your Name
Your Email Address
Your Review

Note: HTML is not translated!

Rating Bad Good

(Click to show)