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Serine/Threonine-Protein Kinase PAK 4 (PAK4) Antibody

Catalogue No: abx002088
Price: £120.00
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Serine/Threonine-Protein Kinase PAK 4 (PAK4) Antibody

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PAK4 Antibody is a Rabbit Polyclonal antibody against PAK4. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Target PAK4
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human PAK4.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O96013 (UniProt, ExPASy)
UniProt Secondary AC B4DGG6, Q8N4E1, Q8NCH5, Q8NDE3, Q9BU33, Q9ULS8
UniProt Entry Name PAK4_HUMAN
Gene Symbol PAK4
GeneID 10298
KEGG hsa:10298
String 9606.ENSP00000469413
Molecular Weight Calculated MW: 47 kDa, 48 kDa, 54 kDa, 64 kDa
Observed MW: 64 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Serine/Threonine-Protein Kinase PAK 4 (PAK4) Antibody

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