Phosphatidylinositol 3-Kinase Regulatory Subunit Alpha (PIK3R1) Antibody

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position.The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD.This gene encodes the 85 kD regulatory subunit.Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.Alternative splicing of this gene results in four transcript variants encoding different isoforms.

Target	Phosphatidylinositol 3-Kinase Regulatory Subunit Alpha (PIK3R1)
Clonality	Monoclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human PIK3R1 (AA: 159-388) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID	5295
Molecular Weight	83.6 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Phosphatidylinositol 3-Kinase Regulatory Subunit Alpha (PIK3R1)

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