Phosphatidylinositol 3-Kinase Regulatory Subunit Alpha (PIK3R1) Antibody

PIK3R1 Antibody is a Rabbit Polyclonal antibody against PIK3R1. Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

Target	Phosphatidylinositol 3-Kinase Regulatory Subunit Alpha (PIK3R1)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human PI3 Kinase p85 alpha.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P27986 (UniProt, ExPASy)
UniProt Entry Name	P85A_HUMAN
Gene Symbol	PIK3R1
GeneID	5295
NCBI Accession	NP_852664.1
KEGG	hsa:5295
String	9606.ENSP00000428056
Molecular Weight	Calculated MW: 84 kDa Observed MW: 85 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Phosphatidylinositol 3-Kinase Regulatory Subunit Alpha (PIK3R1)

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