PLB (pT17) Antibody

Catalogue No: abx032077
Price: £20.00
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PLB (pT17) Antibody

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Phospholamban (PLB) is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases; whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.

Target PLB (pT17)
Reactivity Human
Host Rabbit
Clonality Polyclonal
Tested Applications DB
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Immunogen Human PLB (phospho-Thr17).
Purification Purified Rabbit Polyclonal Antibody.
Isotype IgG
Conjugation Unconjugated
Specificity This PLB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T17 of human PLB.
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot P26678
Buffer PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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