Serum Paraoxonase / Arylesterase 1 (PON1) Antibody

Catalogue No: abx001187
Price: £260.00
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Serum Paraoxonase / Arylesterase 1 (PON1) Antibody

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PON1 Antibody is a Rabbit Polyclonal antibody against PON1. Paroxon is an organophosphorus anticholinesterase compound, used topically in the treatment of glaucoma. It is produced in vivo in mammals by microsomal oxidation of the insecticide parathion. Parathion is inert until transformed to paroxon. Paroxonase or PON is an arylesterase that is capable of hydrolyzing paroxon to produce p-nitrophenol. PONs are nonspecific and their classification is based not only on substrate specificity but also on tissue distribution, inhibition properties and physicochemical characteristics such as electrophoretic mobility and molecular weight. In contrast to PON1, which is expressed mainly in the liver, PON2 is expressed in a variety of mouse tissues, including the pancreas. PON3 is a associated with the high density lipoprotein fraction of serum. The genes which encode PON1-3 are physically linked and map to human chromosome 7q21.3.

Target PON1
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/200 - 1/500, IHC: 1/20 - 1/50, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human PON1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC P27169 (UniProt, ExPASy)
UniProt Secondary AC B2RA40, Q16052, Q6B0J6, Q9UCB1
UniProt Entry Name PON1_HUMAN
Gene Symbol PON1
GeneID 5444
KEGG hsa:5444
String 9606.ENSP00000222381
Molecular Weight Calculated MW: 39 kDa
Observed MW: 40 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Serum Paraoxonase / Arylesterase 1 (PON1) Antibody

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