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POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody

Catalogue No: abx002087
Price: £190.00
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POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody

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POU5F1 Antibody is a Rabbit Polyclonal antibody against POU5F1. This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Target POU Class 5 Homeobox 1 (OCT4/POU5F1)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human POU5F1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q01860 (UniProt, ExPASy)
UniProt Entry Name PO5F1_HUMAN
Gene Symbol POU5F1
GeneID 5460
KEGG hsa:5460
String 9606.ENSP00000259915
Molecular Weight Calculated MW: 30 kDa, 38 kDa
Observed MW: 39 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody

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