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Peroxisome Proliferator Activated Receptor Alpha (PPARA) Antibody

Catalogue No: abx002244
Price: £190.00
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Peroxisome Proliferator Activated Receptor Alpha (PPARA) Antibody

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PPARA Antibody is a Rabbit Polyclonal antibody against Peroxisome Proliferator Activated Receptor Alpha (PPARA). Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

Target Peroxisome Proliferator Activated Receptor Alpha
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human PPARA.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q07869 (UniProt, ExPASy)
UniProt Secondary AC B0G0X3, Q16241, Q6I9S0, Q92486, Q92689, Q9Y3N1
UniProt Entry Name PPARA_HUMAN
Gene Symbol PPARA
GeneID 5465
KEGG hsa:5465
String 9606.ENSP00000385523
Molecular Weight Calculated MW: 18 kDa, 52 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Peroxisome Proliferator Activated Receptor Alpha (PPARA) Antibody

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