Peroxisome Proliferator Activated Receptor Alpha (PPARA) Antibody

PPARA Antibody is a Rabbit Polyclonal antibody against Peroxisome Proliferator Activated Receptor Alpha (PPARA). Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

Target	Peroxisome Proliferator Activated Receptor Alpha (PPARA)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human PPARα.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q07869 (UniProt, ExPASy)
UniProt Secondary AC	B0G0X3, Q16241, Q6I9S0, Q92486, Q92689, Q9Y3N1
UniProt Entry Name	PPARA_HUMAN
Gene Symbol	PPARA
GeneID	5465
NCBI Accession	NP_001001928.1
KEGG	hsa:5465
String	9606.ENSP00000385523
Molecular Weight	Calculated MW: 52 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Peroxisome Proliferator Activated Receptor Alpha (PPARA)

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