Snail Family Transcriptional Repressor 2 / SLUG (SNAI2) Antibody

SNAI2 Antibody is a Rabbit Polyclonal antibody against SNAI2. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

Target	Snail Family Transcriptional Repressor 2 / SLUG (SNAI2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human Slug.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43623 (UniProt, ExPASy)
UniProt Secondary AC	B2R6P6, Q53FC1
UniProt Entry Name	SNAI2_HUMAN
Gene Symbol	SNAI2
GeneID	6591
NCBI Accession	NP_003059.1
KEGG	hsa:6591
String	9606.ENSP00000380034
Molecular Weight	Calculated MW: 30 kDa Observed MW: 30 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Snail Family Transcriptional Repressor 2 / SLUG (SNAI2)

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