Paxillin (PXN) Antibody

Catalogue No: abx000707
Price: £260.00
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PXN Antibody is a Rabbit Polyclonal antibody against PXN. PXN (paxillin) is a 68 kDa scaffold protein that interacts with multiple structural and signaling proteins and regulates cell adhesion, migration, proliferation, and apoptosis. PXN is thought to play an important role in tumor migration, invasion, and metastasis (21045234). PXN has been identified as a direct substrate of protein tyrosine phosphatase receptor-type T (PTPRT), a potent tumor suppressor gene. Increased phospho-PXN at tyrosine residue 88 (Y88) has been found as a common feature of human colon cancers (20133777).

Target PXN
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PXN.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC P49023 (UniProt, ExPASy)
UniProt Secondary AC B2RAI3, B7ZMB4, O14970, O14971, O60360, Q5HYA4
UniProt Entry Name PAXI_HUMAN
Gene Symbol PXN
GeneID 5829
String 9606.ENSP00000267257
Molecular Weight Calculated MW: 46 kDa, 60 kDa, 64 kDa, 66 kDa
Observed MW: 60 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Paxillin (PXN) Antibody

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