RPS6 (pS235) Antibody

Catalogue No: abx000279
Price: £230.00
(Size: 50 µl)
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RPS6 (pS235) Antibody

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RPS6 (pS235) Antibody is a Rabbit Polyclonal antibody against RPS6 (pS235). Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Target RPS6 (pS235)
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S235 of human RPS6.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P62753 (UniProt, ExPASy)
UniProt Secondary AC P08227, P10660, Q4VBY7, Q8N6Z7
UniProt Entry Name RS6_HUMAN
Gene Symbol RPS6
GeneID 6194
KEGG hsa:6194
String 9606.ENSP00000369757
Molecular Weight Calculated MW: 28 kDa
Observed MW: 29 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on RPS6 (pS235) Antibody

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