Runt Related Transcription Factor (RUNX1) Antibody

Catalogue No: abx016071
Price: £290.00
(Size: 100 µl)

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Datasheet SDS
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters.The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis.Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia.Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart.Highest levels in thymus, bone marrow and peripheral blood.

Target RUNX1
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthesized peptide of human RUNX1.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q01196 (UniProt, ExPASy)
UniProt Entry Name RUNX1_HUMAN
Gene Symbol RUNX1
GeneID 861
OMIM 151385
HGNC 10471
KEGG hsa:861
Ensembl ENSG00000159216
String 9606.ENSP00000300305
Molecular Weight 55 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on RUNX1

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