Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) S Protein RBD is a recombinant protein expressed in Mammalian cells.
The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.
| Target |
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) S Protein RBD |
| Origin |
Virus |
| Expression |
Recombinant |
| Tested Applications |
ELISA, SDS-PAGE, WB |
| Host |
Mammalian cells |
| Recommended dilutions |
Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation |
Unconjugated |
| Form |
Liquid |
| Purity |
> 95% (SDS-PAGE) |
| Purification |
0.2 µm filtered. |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| NCBI Accession |
QHD43416.1
|
| Sequence Fragment |
Asn331-Val524 |
| Sequence |
NITNLCPFGE VFNATRFASV YAWNRKRISN CVADYSVLYN SASFSTFKCY GVSPTKLNDL CFTNVYADSF VIRGDEVRQI APGQTGKIAD YNYKLPDDFT GCVIAWNSNN LDSKVGGNYN YLYRLFRKSN LKPFERDIST EIYQAGSTPC NGVEGFNCYF PLQSYGFQPT NGVGYQPYRV VVLSFELLHA PATVPRDCGC KPCICTVPEV SSVFIFPPKP KDVLTITLTP KVTCVVVDIS KDDPEVQFSW FVDDVEVHTA QTQPREEQFN STFRSVSELP IMHQDWLNGK EFKCRVNSAA FPAPIEKTIS KTKGRPKAPQ VYTIPPPKEQ MAKDKVSLTC MITDFFPEDI TVEWQWNGQP AENYKNTQPI MDTDGSYFVY SKLNVQKSNW EAGNTFTCSV LHEGLHNHHT EKSLSHSPGK |
| Tag |
C-terminal mFc tag. |
| Buffer |
PBS, pH 7.4. |
| Endotoxin Level |
< 0.1 ng/µg (1 IEU/µg) as determined by LAL test. |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
Research Articles on SARS-CoV-2/COVID-19 S Protein RBD
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