Serpin H1 (SERPINH1) Antibody

SERPINH1 Antibody is a Rabbit Polyclonal antibody against SERPINH1. This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Target	Serpin H1 (SERPINH1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 350-418 of human HSP47/HSP47/SERPINH1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P50454 (UniProt, ExPASy)
UniProt Secondary AC	B3KVJ3, P29043, Q5XPB4, Q6NSJ6, Q8IY96, Q9NP88
UniProt Entry Name	SERPH_HUMAN
Gene Symbol	SERPINH1
GeneID	871
NCBI Accession	NP_001193943.1
KEGG	hsa:871
String	9606.ENSP00000434412
Molecular Weight	Calculated MW: 46 kDa Observed MW: 46 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Serpin H1 (SERPINH1)

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