Splicing Factor 3B Subunit 3 (SF3B3) Antibody

Catalogue No: abx001873
Price: £260.00
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Splicing Factor 3B Subunit 3 (SF3B3) Antibody

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SF3B3 Antibody is a Rabbit Polyclonal antibody against SF3B3. This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

Target SF3B3
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SF3B3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC Q15393 (UniProt, ExPASy)
UniProt Secondary AC Q6NTI8, Q96GC0, Q9BPY2, Q9UFX7, Q9UJ29
UniProt Entry Name SF3B3_HUMAN
Gene Symbol SF3B3
GeneID 23450
KEGG hsa:23450
String 9606.ENSP00000305790
Molecular Weight Calculated MW: 30 kDa, 44 kDa, 135 kDa
Observed MW: 130 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Splicing Factor 3B Subunit 3 (SF3B3) Antibody

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