Synuclein Alpha (SNCA) Antibody

Catalogue No: abx000525
Price: £260.00
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SNCA Antibody is a Rabbit Polyclonal antibody against SNCA. SNCA, also named as NACP, PARK1 and Alpha-synuclein, belongs to the synuclein family. It may be involved in the regulation of dopamine release and transport. SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. The deposition of aggregated SNCa is the pathological hallmark of Lewy body disease, which includes Parkinson’s disease (PD), diffuse Lewy body disease (DLBD), and Lewy body variant of Alzheimer’s disease (LBV).(PMID:21056999) This antibody can recognize all the isoforms of SNCA.

Target SNCA
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC, FCM
Recommended dilutions WB: 1/200 - 1/2000, IHC: 1/50 - 1/200, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant fusion protein of human SNCA.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Store at 4 °C.
Molecular Weight Calculated MW: 11 kDa/13 kDa/14 kDa
Observed MW: 16 kDa
Swiss Prot P37840
GeneID 6622
Gene Symbol SNCA
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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