Alpha Synuclein (SNCA) Antibody

Catalogue No: abx000525
Price: £260.00
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SNCA Antibody is a Rabbit Polyclonal antibody against SNCA. SNCA, also named as NACP, PARK1 and Alpha-synuclein, belongs to the synuclein family. It may be involved in the regulation of dopamine release and transport. SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. The deposition of aggregated SNCa is the pathological hallmark of Lewy body disease, which includes Parkinson’s disease (PD), diffuse Lewy body disease (DLBD), and Lewy body variant of Alzheimer’s disease (LBV).(PMID:21056999) This antibody can recognize all the isoforms of SNCA.

Target Alpha Synuclein (SNCA)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, FCM
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000, IHC: 1/50 - 1/200, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human SNCA.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC P37840 (UniProt, ExPASy)
UniProt Secondary AC A8K2A4, Q13701, Q4JHI3, Q6IAU6
Gene Symbol SNCA
GeneID 6622
Molecular Weight Calculated MW: 11 kDa, 13 kDa, 14 kDa
Observed MW: 16 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Alpha Synuclein (SNCA) Antibody

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