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SNCA (pY125) Antibody

Catalogue No: abx000293
Price: £220.00
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SNCA (pY125) Antibody

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SNCA (pY125) Antibody is a Rabbit Polyclonal antibody against SNCA (pY125). Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

Target SNCA (pY125)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y125 of human SNCA.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P37840 (UniProt, ExPASy)
UniProt Secondary AC A8K2A4, Q13701, Q4JHI3, Q6IAU6
Gene Symbol SNCA
GeneID 6622
Molecular Weight Calculated MW: 11 kDa, 13 kDa, 14 kDa
Observed MW: 18 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on SNCA (pY125) Antibody

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