Suppressors of Cytokine Signaling 3 (SOCS3) Antibody

Catalogue No: abx000829
Price: £120.00
(Size: 20 µl)
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Suppressors of Cytokine Signaling 3 (SOCS3) Antibody

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SOCS3 Antibody is a Rabbit Polyclonal antibody against SOCS3. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Target SOCS3
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human SOCS3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O14543 (UniProt, ExPASy)
UniProt Secondary AC O14509
UniProt Entry Name SOCS3_HUMAN
Gene Symbol SOCS3
GeneID 9021
KEGG hsa:9021
String 9606.ENSP00000330341
Molecular Weight Calculated MW: 24 kDa
Observed MW: 28 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.84 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Suppressors of Cytokine Signaling 3 (SOCS3) Antibody

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