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SYN1 (pS549) Antibody

Catalogue No: abx000505
Price: £220.00
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SYN1 (pS549) Antibody is a Rabbit Polyclonal antibody against SYN1 (pS549). This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Target SYN1 (pS549)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S549 of human SYN1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P17600 (UniProt, ExPASy)
UniProt Secondary AC B1AJQ1, O75825, Q5H9A9
UniProt Entry Name SYN1_HUMAN
Gene Symbol SYN1
GeneID 6853
String 9606.ENSP00000295987
Molecular Weight Calculated MW: 70 kDa, 74 kDa
Observed MW: 74 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on SYN1 (pS549) Antibody

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