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Transcription Factor E2-Alpha (TCF3) Antibody

Catalogue No: abx000739
Price: £260.00
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TCF3 Antibody is a Rabbit Polyclonal antibody against TCF3. This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Target TCF3
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC, FCM
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human TCF3.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at 2°C to 8°C upon receipt.
Molecular Weight Calculated MW: 67 kDa, 68 kDa
Observed MW: 105 kDa
Swiss Prot P15923
GeneID 6929
Gene Symbol TCF3
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Transcription Factor E2-Alpha (TCF3) Antibody

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