Methylcytosine Dioxygenase TET3 (TET3) Antibody

TET3 Antibody is a Rabbit Polyclonal antibody against TET3. TET3 (tet oncogene family member 3) is a 1,660 amino acid protein that belongs to the TET family and is expressed in both fetal and adult brain, as well as in muscle, colon and adrenal gland tissue. Existing as multiple alternatively spliced isoforms, TET3 may play a role in myeloid malignancies and overall tumor formation and metastasis. The gene encoding TET3 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alström syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

Target	TET3
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IP
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/500, IP: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide of human TET3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC	O43151 (UniProt, ExPASy)
UniProt Secondary AC	A6NEI3, K9JJH7, Q86Z24, Q8TBM9
UniProt Entry Name	TET3_HUMAN
Gene Symbol	TET3
GeneID	200424
KEGG	hsa:200424
String	9606.ENSP00000386869
Molecular Weight	Calculated MW: 77 kDa, 166 kDa, 179 kDa Observed MW: 125 kDa
Buffer	PBS, pH 7.3, 0.02% sodium azide.
Concentration	> 1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on TET3

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