Methylcytosine Dioxygenase TET3 (TET3) Antibody

Catalogue No: abx002256
Price: £270.00
(Size: 200 µl)
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TET3 Antibody is a Rabbit Polyclonal antibody against TET3. TET3 (tet oncogene family member 3) is a 1,660 amino acid protein that belongs to the TET family and is expressed in both fetal and adult brain, as well as in muscle, colon and adrenal gland tissue. Existing as multiple alternatively spliced isoforms, TET3 may play a role in myeloid malignancies and overall tumor formation and metastasis. The gene encoding TET3 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alström syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

Target TET3
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IP
Host Rabbit
Recommended dilutions WB: 1/200 - 1/500, IP: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human TET3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC O43151 (UniProt, ExPASy)
UniProt Secondary AC A6NEI3, K9JJH7, Q86Z24, Q8TBM9
UniProt Entry Name TET3_HUMAN
Gene Symbol TET3
GeneID 200424
KEGG hsa:200424
String 9606.ENSP00000386869
Molecular Weight Calculated MW: 77 kDa, 166 kDa, 179 kDa
Observed MW: 125 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on TET3

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