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Transforming Growth Factor Beta 1 (TGFB1) Antibody

Catalogue No: abx000042
Price: £160.00
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Transforming Growth Factor Beta 1 (TGFB1) Antibody

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TGFB1 Antibody is a Mouse Monoclonal antibody against TGFB1. This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

Target TGFB1
Clonality Monoclonal
Reactivity Human
Tested Applications WB, IHC, FCM
Host Mouse
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, FCM: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TGFB1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01137 (UniProt, ExPASy)
UniProt Secondary AC A8K792, Q9UCG4
UniProt Entry Name TGFB1_HUMAN
Gene Symbol TGFB1
GeneID 7040
KEGG hsa:7040
String 9606.ENSP00000221930
Molecular Weight Calculated MW: 44 kDa
Observed MW: 40 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Transforming Growth Factor Beta 1 (TGFB1) Antibody

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