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Toll Like Receptor 4 (TLR4) Antibody

Catalogue No: abx001921
Price: £260.00
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Toll Like Receptor 4 (TLR4) Antibody

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TLR4 Antibody is a Rabbit Polyclonal antibody against TLR4. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

Target Toll Like Receptor 4 (TLR4)
Clonality Polyclonal
Reactivity Human
Tested Applications WB, FCM
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human TLR4.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC O00206 (UniProt, ExPASy)
Gene Symbol TLR4
GeneID 7099
Molecular Weight Calculated MW: 73 kDa, 91 kDa, 95 kDa
Observed MW: 97 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Toll Like Receptor 4 (TLR4) Antibody

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