Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) Antibody

TNFRSF10C Antibody is a Rabbit Polyclonal antibody against TNFRSF10C. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

Target	Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C)
Clonality	Polyclonal
Reactivity	Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 150-238 of human TNFRSF10C.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O14798 (UniProt, ExPASy)
UniProt Secondary AC	O14755, Q08AS6, Q6FH98, Q6UXM5
UniProt Entry Name	TR10C_HUMAN
Gene Symbol	TNFRSF10C
GeneID	8794
NCBI Accession	NP_003832.2
KEGG	hsa:8794
String	9606.ENSP00000349324
Molecular Weight	Calculated MW: 27 kDa Observed MW: 27 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C)

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