Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) Antibody

Catalogue No: abx001051
Price: £120.00
(Size: 20 µl)
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Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) Antibody

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TNFRSF10C Antibody is a Rabbit Polyclonal antibody against TNFRSF10C. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.

Target Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TNFRSF10C.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O14798 (UniProt, ExPASy)
UniProt Secondary AC O14755, Q08AS6, Q6FH98, Q6UXM5
UniProt Entry Name TR10C_HUMAN
Gene Symbol TNFRSF10C
GeneID 8794
KEGG hsa:8794
String 9606.ENSP00000349324
Molecular Weight Calculated MW: 27 kDa
Observed MW: 27 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) Antibody

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