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TNF Receptor-Associated Factor 3 (TRAF3) Antibody

Catalogue No: abx000883
Price: £120.00
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TNF Receptor-Associated Factor 3 (TRAF3) Antibody

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TRAF3 Antibody is a Rabbit Polyclonal antibody against TRAF3. TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1, CD40 receptor-associated factor 1(CRAF1), CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes, TRAF3 promote 'Lys-63'-linked ubiquitination of target proteins. Moreover, TRAF3 undergoes both 'Lys-48'-linked and 'Lys-63'-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1, OTUB2 and OTUD5.

Target TRAF3
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/200 - 1/1000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TRAF3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13114 (UniProt, ExPASy)
UniProt Secondary AC B7Z8C4, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1
UniProt Entry Name TRAF3_HUMAN
Gene Symbol TRAF3
GeneID 7187
KEGG hsa:718
String 9606.ENSP00000454207
Molecular Weight Calculated MW: 55 kDa, 64 kDa
Observed MW: 70 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on TNF Receptor-Associated Factor 3 (TRAF3) Antibody

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