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Transient Receptor Potential Cation Channel Subfamily V Member 6 (TRPV6) Antibody

Catalogue No: abx001266
Price: £260.00
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TRPV6 Antibody is a Rabbit Polyclonal antibody against TRPV6. The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways. Four subfamilies exist, based on channel domain homology, not activating stimuli: C type (canonical or classical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD). TRPV6 belongs to the V type subfamily, and it facilitates calcium entry across the plasma membrane in pancreas, placenta, and to a lesser extent stomach and kidney tissue. Furthermore, prostate cancer cells overexpress TRPV6, while benign prostate tissues do not express the protein, implying a role for TRPV6 in malignant growth.

Target TRPV6
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human TRPV6.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC Q9H1D0 (UniProt, ExPASy)
UniProt Secondary AC A4D2I8, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296
UniProt Entry Name TRPV6_HUMAN
Gene Symbol TRPV6
GeneID 55503
String 9606.ENSP00000352358
Molecular Weight Calculated MW: 68 kDa, 87 kDa
Observed MW: 70 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Transient Receptor Potential Cation Channel Subfamily V Member 6 (TRPV6) Antibody

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