Transthyretin (TTR) Antibody

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Catalogue No: abx002286
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
TTR Antibody is a Rabbit Polyclonal antibody against TTR. This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009].

Target Transthyretin (TTR)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications IF/ICC
Host Rabbit
Recommended dilutions IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human TTR.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P02766 (UniProt, ExPASy)
UniProt Secondary AC Q549C7, Q6IB96, Q9UBZ6, Q9UCM9
UniProt Entry Name TTHY_HUMAN
Gene Symbol TTR
GeneID 7276
KEGG hsa:7276
String 9606.ENSP00000237014
Molecular Weight Calculated MW: 16 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Transthyretin (TTR)


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