Thioredoxin (TXN) Antibody

Catalogue No: abx000749
Price: £260.00
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TXN Antibody is a Rabbit Polyclonal antibody against TXN. TXN, TRDX, TRX, TRX1, ADF and SASP, belongs to the thioredoxin family. It participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. TXN plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. TXN induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.This antibody is specific to TXN.

Target TXN
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human TXN.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC P10599 (UniProt, ExPASy)
UniProt Secondary AC B1ALW1, O60744, Q53X69, Q96KI3, Q9UDG5
UniProt Entry Name THIO_HUMAN
Gene Symbol TXN
GeneID 7295
KEGG hsa:729
String 9606.ENSP00000363641
Molecular Weight Calculated MW: 9 kDa, 11 kDa
Observed MW: 12 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Thioredoxin (TXN) Antibody

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