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Ubiquitin Carboxyl-Terminal Hydrolase 2 (USP2) Antibody

Catalogue No: abx001237
Price: £260.00
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USP2 Antibody is a Rabbit Polyclonal antibody against USP2. This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Target USP2
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/200 - 1/500, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human USP2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC O75604 (UniProt, ExPASy)
UniProt Secondary AC B0YJB8, E9PPM2, Q8IUM2, Q8IW04, Q96MB9, Q9BQ21
UniProt Entry Name UBP2_HUMAN
Gene Symbol USP2
GeneID 9099
KEGG hsa:909
String 9606.ENSP00000260187
Molecular Weight Calculated MW: 40 kDa, 41 kDa, 45 kDa, 68 kDa
Observed MW: 68 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Ubiquitin Carboxyl-Terminal Hydrolase 2 (USP2) Antibody

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