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Mouse Vinculin (VCL) Protein
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Catalogue No: abx691916
Price:
US$1,029.50
(Size: 50 µg)
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Vinculin (VCL) Protein is a recombinant Mouse protein expressed in HEK293 cells. Vinculin (VCL) is a cytoskeletal protein that is closely related to both cell-matrix interactions and cell-cell junctions. In focal adhesion plaques, VCL is a membrane-cytoskeletal protein involved in linkage of integrin adhesion molecules to the actin cytoskeleton. This protein has multi-ligand properties and can interact with a number of microfilament associated proteins, such as talin, a-actinin, and paxillin, which reportedly bind to either the head or tail domains of vinculin.
Research Articles on Vinculin (VCL)
| Target | Vinculin (VCL) |
| Research Area | Metabolic Pathways, Developmental Science, Bone Metabolism |
| Origin | Mouse |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | HEK293 cells |
| Activity | Not tested |
| Purity | > 90% (SDS-PAGE) |
| Reconstitution | Reconstitute in sterile H2O to make a stock solution of 0.25 mg/ml. Do not vortex. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | The validity for this protein is 12 months. |
| Stability | Stable when stored at 2-8°C for up to 1 week. Reconstituted aliquots are stable at < -20°C for up to 3 months. |
| UniProt Primary AC | Q64727 (UniProt, ExPASy) |
| UniProt Entry Name | VINC_MOUSE |
| Gene Symbol | VCL |
| NCBI Accession | NP_033528.3 |
| Molecular Weight | Calculated MW: 118.2 kDa Observed MW (SDS-PAGE): 118 kDa |
| Sequence Fragment | Met1-Gln1066 |
| Tag | C-terminal His tag |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4, containing 5% Trehalose, 5% Mannitol and 0.01% Tween-80. |
| Endotoxin Level | < 1.0 EU per µg (LAL method). |
| Availability | Shipped within 5-15 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
| Directions for use | Centrifuge before opening to ensure complete recovery of vial contents. |