ATP Binding Cassette Subfamily B Member 7 (ABCB7) Antibody
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Catalogue No: abx032688
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(Size: 80 µl)
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Datasheet SDS
The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.
Research Articles on ATP Binding Cassette Subfamily B Member 7 (ABCB7)
| Target | ATP Binding Cassette Subfamily B Member 7 (ABCB7) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 718-746 amino acids from the C-terminal region of human ABCB7. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O75027 (UniProt, ExPASy) |
| UniProt Secondary AC | G3XAC4, O75345, Q5VWY7, Q5VWY8, Q9BRE1, Q9UND1, Q9UP01 |
| UniProt Entry Name | ABCB7_HUMAN |
| Gene Symbol | ABCB7 |
| GeneID | 22 |
| OMIM | 300135 |
| NCBI Accession | NP_001258625.1 NM_001271696.1 |
| HGNC | 48 |
| KEGG | hsa:22 |
| Ensembl | ENSG00000131269 |
| String | 9606.ENSP00000253577 |
| Molecular Weight | Calculated MW: 82.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat ABCB7. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |