Acid-Sensing Ion Channel 3 (ACCN3) Antibody
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Catalogue No: abx030787
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium. Alternative splicing of this gene generates three transcript variants encoding distinct isoforms.
Research Articles on Acid-Sensing Ion Channel 3 (ACCN3)
| Target | Acid-Sensing Ion Channel 3 (ACCN3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human ACCN3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9UHC3 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R9V0, O60263, O75906, Q59FN9, Q9UER8, Q9UHC4 |
| UniProt Entry Name | ASIC3_HUMAN |
| Gene Symbol | ASIC3 |
| String | 9606.ENSP00000297512 |
| Molecular Weight | Calculated MW: 58.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |