Acid-Sensing Ion Channel 4 (ACCN4) Antibody
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Catalogue No: abx028869
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.
Research Articles on Acid-Sensing Ion Channel 4 (ACCN4)
| Target | Acid-Sensing Ion Channel 4 (ACCN4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human ACCN4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q96FT7 (UniProt, ExPASy) |
| UniProt Secondary AC | Q53SB7, Q6GMS1, Q6PIN9, Q9NQA4 |
| UniProt Entry Name | ASIC4_HUMAN |
| KEGG | hsa:55515 |
| String | 9606.ENSP00000326627 |
| Molecular Weight | Calculated MW: 70.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |