ATP-Citrate Synthase (ACLY) Antibody
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Catalogue No: abx010428
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US$427.75
(Size: 100 µl)
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Datasheet SDS
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.
Research Articles on ATP-Citrate Synthase (ACLY)
| Target | ATP-Citrate Synthase (ACLY) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse, Monkey, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/50, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human ACLY (AA: 306-502) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P53396 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DIM0, B4E3P0, Q13037, Q9BRL0 |
| UniProt Entry Name | ACLY_HUMAN |
| GeneID | 47 |
| KEGG | hsa:47 |
| String | 9606.ENSP00000253792 |
| Molecular Weight | 125 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |