Aldehyde Dehydrogenase 5 Family Member A1 (ALDH5A1) Antibody

ALDH5A1 belongs to the aldehyde dehydrogenase family of proteins. This protein functions as a mitochondrial NAD (+) dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties.

Target	Aldehyde Dehydrogenase 5 Family Member A1 (ALDH5A1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 128-157 amino acids from the N-terminal region of human ALDH5A1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51649 (UniProt, ExPASy)
UniProt Secondary AC	B2RD26, G5E949, Q546H9, Q8N3W6
UniProt Entry Name	SSDH_HUMAN
KEGG	hsa:7915
String	9606.ENSP00000314649
Molecular Weight	Calculated MW: 57.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aldehyde Dehydrogenase 5 Family Member A1 (ALDH5A1)

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