Anti-Mullerian Hormone Receptor Type 2 (AMHR2) Antibody
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Catalogue No: abx033184
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(Size: 80 µl)
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Datasheet SDS
The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
Research Articles on Anti-Mullerian Hormone Receptor Type 2 (AMHR2)
| Target | Anti-Mullerian Hormone Receptor Type 2 (AMHR2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human AMHR2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q16671 (UniProt, ExPASy) |
| UniProt Secondary AC | A0AVE1, B9EGB7, E9PGD2, F8W1D2, Q13762, Q647K2 |
| UniProt Entry Name | AMHR2_HUMAN |
| NCBI Accession | NP_001158162.1 NP_001158163.1 NP_065434.1 |
| KEGG | hsa:269 |
| String | 9606.ENSP00000257863 |
| Molecular Weight | Calculated MW: 62.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rabbit AMHR2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |