Bcl2-Associated Agonist Of Cell Death (BAD) Antibody
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Catalogue No: abx011755
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US$420.50
(Size: 100 µg)
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Datasheet SDS
Bcl2-Associated Agonist Of Cell Death (BAD) Antibody is a Rabbit Polyclonal antibody for the detection of BAD. The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Research Articles on Bcl2-Associated Agonist Of Cell Death (BAD)
| Target | Bcl2-Associated Agonist Of Cell Death (BAD) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | BCL2-associated agonist of cell death |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q92934 (UniProt, ExPASy) |
| UniProt Secondary AC | O14803, Q6FH21 |
| UniProt Entry Name | BAD_HUMAN |
| Gene Symbol | BAD |
| GeneID | 572 |
| OMIM | 603167 |
| HGNC | 936 |
| KEGG | hsa:572 |
| Ensembl | ENSG00000002330 |
| String | 9606.ENSP00000378040 |
| Molecular Weight | Observed MW: 18-25 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |